CBGa And Melatonin

A sound sleep is possible

Sleep-related disorders are becoming more common. It’s a serious issue because lack of sleep can quickly diminish overall health and quality of life.

People struggle to fall or remain asleep due to chronic pain, inflammation, anxiety disorders, and other disease conditions. Sleep-inducing drugs come with severe side effects and may even worsen the situation over time. However many people are finding a solution in CBGa, CBD and CBN, and other natural remedies. 

Information from our previous article shows that about 70 million Americans suffer from sleep-related diseases triggered by chronic diseases, poor mental health, injuries, poor quality of life, increased screen time, and deterioration of general well-being. Statistics from the University of Pennsylvania School of Medicine show that one out of four Americans develops acute insomnia each year. 

Treating sleep-related disorders today consists in medical treatment and homemade remedies like aromatherapy, melatonin, and white noise. So ,anecdotally, it appears cannabinoids can help but research is ongoing. In fact, cannabis (specifically THC) may inhibit healthy sleep. This article will explain the possible relationship between Cannabinoids and melatonin (the sleep hormone) and how they impact sleep. 

What is Melatonin?

Melatonin is a hormone that controls your natural sleep-wake cycle. At night, melatonin levels in the bloodstream are at their peak, mainly because darkness stimulates their production – a key turn in the circadian rhythm. 

Melatonin supplements are also more and more common. These are produced from animals and microorganisms or synthesized in the laboratory for self-treatment of sleep-related disorders. 

How Does Melatonin Work?

Melatonin can affect the sleep/wake cycle and sleep-promotion actions through a particular regulation of both the melatonin 1a and melatonin 1b receptors. The receptors are the primary melatonin receptors in human beings and most mammals.

Also, this is why researchers suggest that melatonin supplements, which artificially boost melatonin levels, can offer some relief against insomnia, delayed sleep phase syndrome (DSPS), and jet lag. 

In contrast to other sleep medications, Melatonin supplements have little to no side effects like addiction or reduced response after continuous usage. Nevertheless, experts suggest that melatonin is generally safer for short-term use

Many melatonin supplements are readily available as pills and can be ingested orally. Melatonin is most potent when directly absorbed into the bloodstream, like CBD. 

Typical doses of melatonin range from 1mg to 20mg. Note that people should consider starting on a lower dose until they know how their body will respond. 

Although melatonin plays a crucial role in regulating the sleep-wake cycle, it doesn’t send one to sleep effectively. Instead, the hormone alerts the brain of the need to sleep. This is sufficient to help those suffering from minor sleep issues to catch some sleep again in rare cases. Therefore, melatonin on its own might be suitable for some people’s needs, but a wide majority of those suffering from sleep disorders require something that is significantly more potent. 

The Science behind CBGa and Sleep Patterns 

We must discuss what CBD is before we talk about why you would combine CBD and melatonin as a way to have a better sleep. 

Small doses of cannabinoids like CBD and CBGa have been shown to improve sleep in both animal and human test subjects. More research studies have discovered the relationship between Cannabinoid therapy and sleep patterns. This may explain the safety level of combining CBGa and hormones like melatonin. 

The researchers in the experiment administered injections consisting of 2.5mg/kg, 10mg/kg, and 40mg//kg of CBD on adult male Wistar rats. They observed the sleep recordings during the dark and light periods for 4 days. 

The researchers found that sleep increased in groups administered with 10mg/kg and 40mg/kg of CBD. The result is compared to subjects who were administered a placebo. The study results speak of the ability of CBD to interact with GABA receptors and serotonin in our brains. 

The interaction between CBD and the sleep cycle shows the level of connection between cannabinoids and melatonin. 

Can You Combine CBG and Melatonin?

The link between melatonin and CBG or any other cannabinoid appears complementary. Nevertheless, several areas of the brain regulate CBG and melatonin. So, yes, you can consume them together.

Melatonin alerts the body that it is time to sleep. CBG tells the brain to recruit the appropriate neurotransmitters to help you remain asleep. This is a powerful tool for people battling sleep-related disorders. Note that falling asleep and staying asleep are separate issues. 

A combination of CBN, CBG, and melatonin in a good proportion can help people sleep peacefully. This is also supported by the fact that cannabinoids are good antioxidants, anti-inflammatory, and antidepressant agents. So rather than just triggering the release and activity of melatonin, they can also take care of underlying conditions that disturb sleep. So the relationship between cannabinoids and melatonin lies in a deeper synergy rather than simply inducing sleepiness. 

Taking CBGa and Melatonin Together: Is It Safe?

To the best of our knowledge, concomitant administration of CBGa and melatonin or combining them in the same product is not harmful. There are little to no side effects associated with this combination too. So until research proves otherwise, we can say it is safe to combine the two. As a way of safety, you must start from small doses and work your way up. This will give you a chance to observe the possible reaction. 


We’ve found the solution to a night of good sleep. It is largely embedded in the right combination of CBN, CBGa, and CBG. These cannabinoids can trigger the release of feel-good hormones, soothe chronic pain and modulate the activities of immune cells. Their powerful antioxidant activity is handy in triggering internal balance and allowing people to stay asleep for as long as possible.

Feel free to check our Life Shop for the best CBGa products in the market.

life Research Co is the exclusive producer of CBGa Rosin. Our formula provides the highest quality CBGa with key terpenes that activate the whole endocannabinoid system in a single dose.